Study Concludes Endometriosis Symptoms Affects Health Related Quality of Life in US Women



Iqra Mumal of shares findings in the “The Burden of endometriosis symptoms on health-related quality of life in women in the United States: a cross-sectional study” that appeared in the Journal of Psychosomatic Obstetrics and Gynecology..


 The study reveals that endometriosis symptoms affect patients Health-Related Quality of Life (HRQL) in terms of both work and relationships. The negative effects on the HROL of women with endometriosis are well-established across multiple studies. Some studies have also been conducted to analyze the effects individual symptoms associated with endometriosis, however, only a few determined the relationship between the severity of endometriosis and HRQL.


A team of researchers from Abbvie, a biopharmaceutical company conducted the cross-sectional study survey online which included study-specific questions and standardized HRQL questions to which respondents chose the symptoms they were currently or previously experienced from a list and also rated the severity of each symptom.


They have also completed EHP-30, the endometriosis health profile—a self-administered test used to measure HRQL of women with endometriosis. Questions in the EHP-30 are divided into five (5) categories of pain, control and powerlessness, emotional well-being, social support and self-image.


At least 75% of the 1,269 women participants with a mean age of 34.3 years, experience symptoms such as pelvic pain, menstrual cramping, anxiety, stress, lower back pain, fatigue weariness and anemia.


EHP-30 scores from the survey respondents ranged from 33.6 to 37.8, indicating moderate HRQL impact on endometriosis patients. Furthermore, EHP-30 scores were significantly higher for women who experience endometriosis-related symptoms than those who didn’t. These scores continued to worsen with an increase in the severity of symptoms. Individual symptoms such as pelvic pain, cramping, irregular periods and general abdominal pain are significantly correlated with negative EHP-30 scores.


The cross-sectional study shows that endometriosis-related symptoms have significant negative impact on women’s HRQL and such increases with the number or severity of symptoms experienced.


The authors conclude that the study “documents the large unmet need in the US to address symptom burden among women with endometriosis”.



By: Marijun Jam Villarino Sy

Chief Finance Officer BUPeriod

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